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KMID : 0861019990140010061
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Korea Journal of Herbology
1999 Volume.14 No. 1 p.61 ~ p.68
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The Effects of Rhei palmati Radix and Rhei undulati Radix on the Blood Lipids and Enzymes of Hypercholesterolic Rats
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Abstract
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The effects of four oriental drugs, Rhei palmati Radix, Rhei palmati Radix Prep., R. undulati Radix, and R. undulati Radix Prep., on the blood lipids and the enzymes of hypercholesterolic rats were analyzed. The results were as follows:
1. The four drugs had significantly decreasing effects on the contents of total cholesterol and LDL0cholesterol in the blood of hypercholesterolic rats.
2. The drugs had no effects on the contents of creatinine, while R. undulati Radix Prep. increased the activity of ACE in the blood of hypercholesterolic rats.
3. The drugs in vitro decreased the activities of lactate dehydrogenase and creatinine kinase. These results indicated that the drugs could have had some effects on the enzymes regulating the lipid metabolism.
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